The Korean Journal of Pharmacology (대한약리학회지)
- Volume 10 Issue 2
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- Pages.63-74
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- 1974
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- 0377-9459(pISSN)
Effect of Hydrocortisone infused into a Renal Artery on the Diuretic Actions of Acetazolamide and Aminophylline
Hydrocortisone의 신동맥 주입이 acetazolamide 및 aminophylline의 이뇨작용에 미치는 영향
- Lee, Jong-Hha (Department of Pharmacology, Catholic Medical College) ;
- Lee, Duck-Hee (Department of Pharmacology, Catholic Medical College) ;
- Cho, Kyu-Chul (Department of Pharmacology, Catholic Medical College)
- Published : 1974.12.30
Abstract
This study was carried out to observe the direct effect of hydrocortisone on renal function by infusing it into a renal artery. Hydrocortisone (5mg/kg) or saline (0.5 ml/kg) was infused directly into the left renal artery of the rabbit, the right kidney was left intact to serve as a control for general action of acetazolamide (10 mg/kg) or aminophylline (10 mg/kg), which was administered intravenously 30 minutes after the direct infusion of pretreated drugs (hydrocortisone or saline). The changes of urine volume, pH, urinary excretion rates of
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