Studies on the Ginseng Plants(I) -Saponins and Sapogenins from American Ginseng Plants-

인삼식물(人蔘植物)에 관(關)한 연구(硏究)(I) -미국인삼(美國人蔘) 사포닌 및 그 비당체(非糖體)-

  • Kim, Jung-Yun (Department of Pharmacology, College of Pharmacology, University of Minnesota) ;
  • Staba, E. John (Department of Pharmacology, College of Pharmacology, University of Minnesota)
  • 김정연 (미네소타대학교 약학대학 생약학교실) ;
  • 이.죤 스태바 (미네소타대학교 약학대학 생약학교실)
  • Published : 1973.12.15

Abstract

The saponins of two- and four-year-old American ginseng plants (Panax quinquefolium L.) (Araliaceae) collected in July and September were studied. American ginseng saponins (panaquilins) differ from Korean ginseng $(Panax ginseng\;C.A.\;M_{EYER})$ saponins (ginsenosides). The American ginseng saponins separated and named were panaquilins A, B, C, D, E-1, E-2, E-3, G-1, G-2, (c) and (d). One-dimensional thin-layer chromatography did not completely separate panaquilin mixture and was subject to misinterpretation. The panaquilins were more accurately separated and identified by the two-dimensional thin-layer method established. Some differences in American ginseng saponins were dependent upon the plant age, time of collection, and part extracted. The American ginseng sapogenin components are panaxadiol (panaquilins B and C), oleanolic acid (panaquilin D) and panaxatriol (panaquilin G-1). The panaquilins E-1, E-2 and E-3 mixture contained both panaxadiol and panaxatriol. The genins of panaquilins A, (c), (d) and G-2 were not identified. In addition, ${\beta}-sitosterol$ and stigmasterol were identified from the root ether extracts.

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