The Korean Journal of Mycology (한국균학회지)

The Korean Society of Mycology (한국균학회)
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Studies on the Antifungal Activities of Siccanin and Azalomycin-F in vitro Tests

수종(數種) 진균류(眞菌類)에 대(對)한 Siccanin 및 Azalomycin-F 항진균작용(抗眞菌作用)의 실험관내(實驗管內) 실험(實驗)

  • Koh, Choon-Myung (Dept. of Microbiology, Yonsei University, College of Medicine) ;
  • Choi, Tae-Joo (Dept. of Microbiology, Yonsei University, College of Medicine) ;
  • Kwon, Sung-Won (Dept. of Microbiology, Yonsei University, College of Medicine) ;
  • Lew, Joon (Dept. of Microbiology, Yonsei University, College of Medicine)
  • 고춘명 (연세대학교 의과대학 미생물학교실) ;
  • 최태주 (연세대학교 의과대학 미생물학교실) ;
  • 권성원 (연세대학교 의과대학 미생물학교실) ;
  • 류준 (연세대학교 의과대학 미생물학교실)
  • Published : 1973.06.30
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Abstract

The discovery of ideal therapeutics of fungal infections are remain a major problems of several mycoses. The antifungal activities of a new antifungal antibiotic named Siccanin and Azalomycin-F studies in vitro against some various species of fungi especially dermatophytes. The antifungal activity tests were performed according to the tube-dilution method and all subcultures were incubated at room temperature for 14 days. Results were obtained as follows: 1. All of the Candida spp. were grow on the various concentration of Siccanin tested but Azalomycin-F were growth inhibited at 7mcg-10mcg per ml. 2. Trichophyton spp. and Microsporum spp. were inhibited for growth at 2mcg-6mcg per ml. and 3mcg-5mcg per ml. concentration of Siccanin and 1mcg-4mcg per ml. of Azalomycin-F. 3. Deep mycoses and some saprophytes were grow on the all tested concentration of Siccania and Azalomycin-F.

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