The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Studies on the Radioimmunoassay of Human Growth Hormone - 1. Evaluation of the method of determination

사람성장(成長)홀몬의 방사면역측정(放射免疫測定)에 관한 연구 - 제I편 사람성장(成長)홀몬의 측정법에 관한 검토

  • Lee, Young-Woo (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lee, Hong-Kyu (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Koh, Chang-Soon (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lee, Mun-Ho (Department of Internal Medicine, College of Medicine, Seoul National University)
  • 이영우 (서울대학교 의과대학 내과학교실) ;
  • 이홍규 (서울대학교 의과대학 내과학교실) ;
  • 고창순 (서울대학교 의과대학 내과학교실) ;
  • 이문호 (서울대학교 의과대학 내과학교실)
  • Published : 1972.07.30
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Abstract

Utilizing the commercial radioimmunoassay kit, the author assayed HGH and evaluated the problems of the method. The method had the sensitivity of 0.5 mug/ml degree and could determine the plasma HGH concentration directly without the help of plasma extraction. Also it was specific for the HGH, when tested by a dilution method using test utilizing the plasma of the acromegalic patient. The author also obtained the $^{125}I$ labelled HGH of specific activity of $156.3{\mu}Ci/{\mu}g$, performing the chloramine-T method.

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