The Korean Journal of Pharmacology (대한약리학회지)

The Korean Society of Pharmacology (대한약리학회)
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The Studies of Component and Pharmacologic Action on Dianthus sinensis L.

구맥(瞿麥) Dianthus sinensis L.의 성분(成分) 및 약리작용(藥理作用)에 관(關)한 연구(硏究) ( I )

  • Han, Dae-Sup (Department of Pharmacology, School of Medicine, Kyung Hee University) ;
  • Ko, Kye-Chang (Department of Pharmacology, School of Medicine, Kyung Hee University) ;
  • Jung, Jee-Chang (Department of Pharmacology, School of Medicine, Kyung Hee University)
  • 한대섭 (경희대학교 의과대학 약리학교실) ;
  • 고계창 (경희대학교 의과대학 약리학교실) ;
  • 정지창 (경희대학교 의과대학 약리학교실)
  • Published : 1972.12.30
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Abstract

The component and pharmacologic action on Dianthus sinensis L. were investigated as follows: 1) The components of Dianthus sinensis L. were suggested 8 kind of components by means of thin layer chromatography and paper chromatography. The one of them were suggested as a steroidal saponin by means of IR-spectrum and Liebermann-Burchard, Salkowiski, $SbCl_3$ reaction. 2) Sodium level in serum were reduced by administration of the sample to the rabbits, while in urine were elevated. 3) Blood sugar level of normal rabbits administered with sample, no significant variation were detected. 4) When the hyperglycemic rabbits treated with alloxan were administered sample, blood-sugar level were significantly decreased than control group.

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