The Korean Journal of Physiology
- 제6권2호
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- Pages.9-17
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- 1972
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- 0300-4015(pISSN)
급성 신장 빈혈이 신장의 유기성 대사에 미치는 영향
Effects of Acute Renal Ischemia on Aerobic Metabolism of Rabbit Kidney Homogenates
- 강석원 (고려대학교 의과대학 생리학교실)
- Kang, Suk-Won (Department of Physiology, Korea University, College of Medicine)
- 발행 : 1972.10.01
초록
This experiment was carried out to investigate systematically how the aerobic metabolic capacity of renal tissue reduced by the effects of a period of induced ischemia. Aerobic metabolic studies were performed on homogenates of cortex and medulla of rabbits. Ischemia was induced by occluding the renal vein or renal artery of the left kidney for an hour. The right kidney used as a paired control. Aerobic metabolism was asesssed by measuring the oxygen consumption using the Warburg's manometric apparatus. The results are summarized as follows: 1. One hour of occlusive ischemia does not increase in the kidney weight in the renal arterial occlusion but increase in the renal venous occlusion. 2. Occlusion of either the renal vein or renal artery for an hour did not reduce to any significant degree the level of endogenous substrate in cortical homogenates as measured the rates of
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