The Korean Journal of Physiology
- Volume 6 Issue 1
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- Pages.1-9
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- 1972
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- 0300-4015(pISSN)
Effect of CO Intoxication on the Pulmonary Surfactant in Rabbits
일산화탄소중독(一酸化炭素中毒)이 가토(家兎) 폐포표면활성물질(肺胞表面活性物質)에 미치는 영향(影響)
- Choo, Young-Eun (Department of Physiology, Kyungbook National University School of Medicine) ;
- Lee, Suck-Kang (Department of Physiology, Kyungbook National University School of Medicine)
- Published : 1972.06.01
Abstract
In order to observe a possible effect of CO intoxication on the activities of surfactant, the rabbit war exposed either to 0.1, 0.2 and 0.4% CO gas for two to six hours or 0. 1% CO gas for two hours daily for 1, 3 and 5 days, and the lung extract was prepared. The tension-area diagram of the lung extract was recorded automatically using the modified Langmuir-wilhelmy balance with a synchronized recording system, and the results were compared with control (i. e. : non-CO gas exposed normal rabbits). The results obtained are summarized as follows: 1. The maximal and minimal surface tensions, width of the tension-area diagram at the surface area of 40% in lung extract, and stability index of the normal rabbit lung extracts were
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