The Korean Journal of Nuclear Medicine (대한핵의학회지)
- Volume 5 Issue 2
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- Pages.41-56
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- 1971
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- 1225-6714(pISSN)
Anemia of Chronic Liver Diseases
만성(慢性) 간질환(肝疾患)의 빈혈상(貧血像)
- Shin, Hyun-Chung (Dept. of Int. Med., College of Medicine, Seoul National University) ;
- Lee, Jhung-Sang (Dept. of Int. Med., College of Medicine, Seoul National University) ;
- Koh, Chang-Soon (Dept. of Int. Med., College of Medicine, Seoul National University) ;
- Lee, Mun-Ho (Dept. of Int. Med., College of Medicine, Seoul National University)
- Published : 1971.12.20
Abstract
The pathogenetic mechanisms of anemia in patients with chronic liver disease were observed. Seventeen patients with moderate to advanced hepatic diseass were studied by various methods. Only patients without previous blood loss were included: 14 had cirrhosis, 2 had active chronic hepatitis, and one had inferior vena cava obstruction with associated liver cirrhosis. The followings were the results: 1. The anemia based on red blood cell count, Hb., and Ht. was found in 76.5-78.6% of the patients. 2. Red cell indices indicated that normo-macrocytic and normochromic anemia was present is the majority of the patients. 3. No evidence of megaloblastic anemia was found on the basis of the morphological examinations. 4. Serum iron, TIBC, % saturation and iron content in the bone marrow indicated that iron deficiency anemia was present in about half of the patients. 5. In the view of the erythrocyte dynamics, primary increase in the red cell destruction was ascribed to the cause of the anemia. 6. Decrease in the red cell survival time was not correlated with MCV, % saturation and S.L. ratio. Also, hemoglobin level was not correlated with MCV, % saturation and
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