The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Radioimmunoassay of Plasma Insulin during Oral Glucose Tolerance Test in Thyrotoxicosis

갑상선(甲狀腺) 기능항진증(機能亢進症)에서의 경구적(經口的) 당부하시험시(糖負荷試驗時) 혈장(血漿) Insulin의 변동(變動)

  • Lee, Hong-Kyu (Dept. Int. Med, College of Medicine, Seoul National University) ;
  • Koh, Chang-Soon (Dept. Int. Med, College of Medicine, Seoul National University) ;
  • Lee, Mun-Ho (Dept. Int. Med, College of Medicine, Seoul National University)
  • 이홍규 (서울대학교 의과대학 내과학교실) ;
  • 고창순 (서울대학교 의과대학 내과학교실) ;
  • 이문호 (서울대학교 의과대학 내과학교실)
  • Published : 1971.06.20
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Abstract

Blood glucose and immunoreactive insulin (IRI) were measured during oral glucose tolerance test in 15 thyrotoxic patients and 8 normal controls, to study the glucose metabolism in thyrotoxicosis. Following were the results; 1. In thyrotoxicosis, there is noticed late rise and late fall of plasma IRI durnig oral glucose tolerance test, like as phenomenon of mild diabetes mellitus. 2. When the thyrotoxic patients were divided into normal and abnormal responsive groups after the level of blood glucose by Wilkerson Criteria, no significant differences in plasma IRI levels were noticed between two groups. 3. This result may be interpreted as relative deficiency of insulin secretion from panceas and suggest genetically related defects.

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