Effects of Various Agents on the Phosphorylase Activity of Rat Kidney

백서 신장 Phosphorylase 활성도에 대한 수종물질의 영향

  • Shin, Suk-Dae (Department of Physiology, Pusan National University School of Medicine) ;
  • Kim, Jung-Han (Department of Physiology, Pusan National University School of Medicine) ;
  • Lee, Sang-Ho (Department of Physiology, Pusan National University School of Medicine)
  • 신석대 (부산대학교 의과대학 생리학교실) ;
  • 김정한 (부산대학교 의과대학 생리학교실) ;
  • 이상호 (부산대학교 의과대학 생리학교실)
  • Published : 1971.12.01

Abstract

The direct effects of various agents on the phosphorylase activity of rat kidney was studied in vitro and the results were summarized as follows. 1. The kidney phosphorylase activity was markedly depressed by iodoacetic acid whereas it was increased by sodium azide. 2. DNP had no effect on the phosphorylase activity, while sodium cyanide slightly increased the activity of the enzyme. 3. Ouabain slightly depressed the phosphorylase activity whereas it was markedly depressed by oligomycin. 4. Vasopressin and histamine markedly increased the phosphorylase activity.

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