Effect of Ether and Halothane Anesthesia on Protein Contents of the Lung and Liver in Rabbits

Ether 및 Halothane 전신마취(全身麻醉)가 가토폐(家兎肺) 및 간조직(肝組織)의 단백량(蛋白量)에 미치는 영향(影響)

In an attempt to observe possible effects of ether and halothane anesthesia on the protein contents of the lung and liver of rabbits, the animal was subjected to the moderato anesthesia with either ether or halothane by non-rebreathing system for one hour, and the protein content of the lung and liver was measured by the method of Lowry et at. using Folin-phenol reagent. The comparison was made with the protein content from the normal rabbits, and the following results were obtained. l) The protein contents of the lung and liver of the normal rabbit were $45.0{\sim}11.5\;mg/gm$ wet wt. and $100.4{\sim}15.1\;mg/gm$ wet wt. respectively. 2) In the ether or halothane anesthesized group, the protein contents of the lung were $57.2{\sim}13.3\;and\;60.3{\sim}7.2$ respectively. 3) In the anesthesia groups with ether and halothane, the protein contents of the liver were $103.4{\sim}10.0\;and\;90.1{\sim}13.0$ respectively. 4) No significant difference in the protein contents of the lung and liver was observed after ether or halothane anesthesia comparing with the normal.