Hemoglobin variant Found in Koreans

한국인(韓國人)을 대상(對象)으로 한 이상혈색소(異常血色素)의 변이형(變異型)에 관(關)한 연구(硏究)

One male in the former group of 2110 Korean males of the Republic of Korea Army stationed Taegu. And two males and one female in the later group of 4590 Korean school children and university students in Seoul and Taejuon were found to have a slow hemoglobin in addition to normal hemoglobin A. In all four subjects the slow component migrated at a rate characteristic of the G hemoglobin. The overall incidence of the variant in the present group of Koreans was low: 4 in 6700 or 0.06 percent. It appears significant that no insistence of hemoglobin E were found among these Korean subjects. Hemoglobin E has been found among numerous ethnic groups of Southeast Asia and the variant most frequently appeared in Chinese subject. By Urea-Starch-Gel Electrophoresis in Alkaline PH and A.I. Chernoff method was demonstrated that another 3 cases of abnormal hemoglobin also were beta-chain variants. This was reconfirmed by Hybridization Experiment with canine hemoglobin. And the results of family test of 3 case of abnormal hemoglobin were heterozygous carrier.