개구리 피부의 세포접착부에 관한 전자 현미경적 연구

Electron Microscopy of the Intercellular Junction of Frog (Rana temporaria) Skin

  • Yoon, J.S. (Electron Microscope Laboratory, Yonsei University, College of Medicine) ;
  • Chang, S.H. (Electron Microscope Laboratory, Yonsei University, College of Medicine) ;
  • Choi, K.D. (Electron Microscope Laboratory, Yonsei University, College of Medicine)
  • 발행 : 1969.09.01

초록

개구리(Rana temperaria) 상피조직의 세포간 접착부위를 전자현미경으로 관찰하였다. 새로운 절편방법을 시도하여 동 부위의 초미세구조를 밝혔으며, 세가지 세포간간 접착방법중 하나인 데스모솜(Desmosome)은 상피세포 원형질막을 따라 절서있고 빈번하게 배열되어 있음을 처음으로 밝혀냈다. 본 연구 및 관찰결과와 관련하여 피부 암세포의 성장기 전 과의 관계를 논의하였다.

Electron microscopy on the skin of young frogs, Rana temporaria, has been carried out with particular reference to cellular attachment sites. For the first time now several technical developments allow a more detailed visualization of the fine structure within the cellular attachment sites as well as making it possible to show the ultra-structural morphology of the junctional complexes, and to demonstrate that the desmosomes are regularly distributed aroand each skin cell, especially in the S. granulosum. The relations of these findings to these of previous investigations concerning the functional, organization of the junctional complexes and to the findings in skin cancer from a cellular adhesion view point have been briefly discussed.

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