대한핵의학회지 (The Korean Journal of Nuclear Medicine)

대한핵의학회 (The Korean Society of Nuclear Medicine)
권호 표지

갑상선종환자(甲狀腺腫患者)의 안병변(眼病變)에 관(關)한 임상적(臨床的) 관찰(觀察)

Clinical Study on the Eye Changes in the Goiter Patients

  • 구인서 (서울대학교 의과대학 내과학교실) ;
  • 이정상 (서울대학교 의과대학 내과학교실) ;
  • 이경자 (서울대학교 의과대학 내과학교실) ;
  • 최근출 (서울대학교 의과대학 내과학교실) ;
  • 안수벽 (서울대학교 의과대학 내과학교실) ;
  • 이장규 (서울대학교 의과대학 내과학교실) ;
  • 이문호 (서울대학교 의과대학 내과학교실)
  • Ku, In-Seo (Dept. of Int. Med., College of Medicine Seoul National University) ;
  • Lee, Jung-Sang (Dept. of Int. Med., College of Medicine Seoul National University) ;
  • Lee, Kyung-Ja (Dept. of Int. Med., College of Medicine Seoul National University) ;
  • Choi, Kuen-Chul (Dept. of Int. Med., College of Medicine Seoul National University) ;
  • Ahn, Soo-Byuk (Dept. of Int. Med., College of Medicine Seoul National University) ;
  • Lee, Chang-Kyu (Dept. of Int. Med., College of Medicine Seoul National University) ;
  • Lee, Mun-Ho (Dept. of Int. Med., College of Medicine Seoul National University)
  • 발행 : 1969.05.25
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초록

742 cases of thyroid diseases treated at Radio-isotope Clinic, Seoul National University Hospital since October 1965 through July 1968 were analyzed. The patients were classified according to eye findings, as to Infiltrative, Non-infiltrative and No ophthalmopathy. Correlations between ophthalmological findings and symptoms, BMR values and $^{131}I$ uptake rate as well as response to medical treatment were carefully reviewed. Results obtained were as follows: 1. Among goitrous patients 44.5% with infiltrative ophthalmopathy, 24.1% with non-infiltrative ophthalmopathy totaling 68.6% of patients with one or more eye findings were found. Exophthalmos (44%) and visual disturbances (44%) comprised the highest incidence among eye signs. Most frequent eye symptoms were lid swelling (17.1%). 2. Female patients were predominant(91%). 3. Of cases with hyperthyroidism, after treatment with antithyroid drugs and radio-iodine therapy, general symptoms were improved in over 74%, whereas ophthalmopathy was not changed and in some cases the eye signs were aggravated. This tendency was more apparent in infiltrative ophthalmopathy. 4. Significant correlations between exophthalmos, BMR values and $^{131}I$ uptake rate were found. Among the patients of same degree of exophthalmos, BMR values and $^{131}I$ uptake rate showed the highest in non-infiltrative ophthalmopathy, moderate in infiltrative ophthalmopathy and the lowest in no ophthalmopathy.

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