The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Clinical Study on the Eye Changes in the Goiter Patients

갑상선종환자(甲狀腺腫患者)의 안병변(眼病變)에 관(關)한 임상적(臨床的) 관찰(觀察)

  • Ku, In-Seo (Dept. of Int. Med., College of Medicine Seoul National University) ;
  • Lee, Jung-Sang (Dept. of Int. Med., College of Medicine Seoul National University) ;
  • Lee, Kyung-Ja (Dept. of Int. Med., College of Medicine Seoul National University) ;
  • Choi, Kuen-Chul (Dept. of Int. Med., College of Medicine Seoul National University) ;
  • Ahn, Soo-Byuk (Dept. of Int. Med., College of Medicine Seoul National University) ;
  • Lee, Chang-Kyu (Dept. of Int. Med., College of Medicine Seoul National University) ;
  • Lee, Mun-Ho (Dept. of Int. Med., College of Medicine Seoul National University)
  • 구인서 (서울대학교 의과대학 내과학교실) ;
  • 이정상 (서울대학교 의과대학 내과학교실) ;
  • 이경자 (서울대학교 의과대학 내과학교실) ;
  • 최근출 (서울대학교 의과대학 내과학교실) ;
  • 안수벽 (서울대학교 의과대학 내과학교실) ;
  • 이장규 (서울대학교 의과대학 내과학교실) ;
  • 이문호 (서울대학교 의과대학 내과학교실)
  • Published : 1969.05.25
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Abstract

742 cases of thyroid diseases treated at Radio-isotope Clinic, Seoul National University Hospital since October 1965 through July 1968 were analyzed. The patients were classified according to eye findings, as to Infiltrative, Non-infiltrative and No ophthalmopathy. Correlations between ophthalmological findings and symptoms, BMR values and $^{131}I$ uptake rate as well as response to medical treatment were carefully reviewed. Results obtained were as follows: 1. Among goitrous patients 44.5% with infiltrative ophthalmopathy, 24.1% with non-infiltrative ophthalmopathy totaling 68.6% of patients with one or more eye findings were found. Exophthalmos (44%) and visual disturbances (44%) comprised the highest incidence among eye signs. Most frequent eye symptoms were lid swelling (17.1%). 2. Female patients were predominant(91%). 3. Of cases with hyperthyroidism, after treatment with antithyroid drugs and radio-iodine therapy, general symptoms were improved in over 74%, whereas ophthalmopathy was not changed and in some cases the eye signs were aggravated. This tendency was more apparent in infiltrative ophthalmopathy. 4. Significant correlations between exophthalmos, BMR values and $^{131}I$ uptake rate were found. Among the patients of same degree of exophthalmos, BMR values and $^{131}I$ uptake rate showed the highest in non-infiltrative ophthalmopathy, moderate in infiltrative ophthalmopathy and the lowest in no ophthalmopathy.

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