Studies on the synthesis of nitrogen mustard derivatives

Nitrogen mustard류의 합성에 관한 연구

  • Chae, Dong-Kyu (College of Pharmacy, Seoul National University) ;
  • Chun, Moon-Woo (College of Pharmacy, Seoul National University) ;
  • Chae, Kun (College of Pharmacy, Seoul National University)
  • Published : 1969.12.01

Abstract

In order to diminish the side effects of nitrogen mustard on cancertherapy, alkyl and heterocyclic radicals were introduced to nitrogen mustard base. The prepared new nitrogen mustard derivtives are N-bis($\beta$-chloroethyl)-2-furamide, 5-nitro-N-bis($\beta$-chloroethyl)-2-furamide and N-bis($\beta$-chloroethyl) ortamide hydrochloride.

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