The Korean Journal of Pharmacology (대한약리학회지)

The Korean Society of Pharmacology (대한약리학회)
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The Effects of Various Drugs on Rat Submaxillary Gland

백서악하선(白鼠顎下腺)에 미치는 수종약물(數種藥物)의 효과(效果)

  • Park, No-Hi (Department of Pharmacology, Woo Sok University Medical College) ;
  • Lim, Han-Young (Department of Pharmacology, Woo Sok University Medical College) ;
  • Koo, Hi-Soo (Department of Pharmacology, Woo Sok University Medical College) ;
  • Lyo, Woon-Don (Department of Pharmacology, Woo Sok University Medical College)
  • 박노희 (우석대학교 의과대학 약리학교실) ;
  • 임한영 (우석대학교 의과대학 약리학교실) ;
  • 구희수 (우석대학교 의과대학 약리학교실) ;
  • 여운돈 (우석대학교 의과대학 약리학교실)
  • Published : 1969.12.30
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Abstract

In order to investigate the effect of autonomic nervous system on salivary gland, the authors have observed the effects of various drugs acting on the autonomic nervous system to the rat submaxillary gland by comparing the changes of gland weight, the amylase activity and various electrolyte contents with control group. The results are as follows; 1. The pilocarpine, physostigmine, norepinephrine, atropine and DMPP increased the rat submaxillary gland weight. 2. The amylase activities of rat submaxillary gland were increased by pilocarpine, physostigmine and norepinephrine, but decreased by atropine and DMPP. 3. Calcium contents of rat submaxillary gland were highly increased by pilocarpine and physostigmine, hut slightly increased by norepinephrine. 4. Magnesium contents of rat submarillary gland were increased by DMPP, but decreased by pilocarpine, physostigmine and norepinephrine. 5. Sodium contents of rat subnaxillary gland were increased by pilocarpine, physostigmine, norepinephrine and DMPP, but decreased by atropine. 6. Potassium contents of rat submaxillary gland were highly increased by atropine, and slightly increased by DMPP and norepinephrine, but decreased by pilocarpine and physostigmine.

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