Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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The Effects of Propylthiouracil on the Metabolic Rate and the Thyroidal Activity in Korean Native Goats

Propylthiouracil이 재래산양(在來山羊)의 대사율(代謝率) 및 갑상선(甲狀腺) 기능(機能)에 미치는 영향

  • Kwun, Jong Kuk (College of Agriculture, Seoul National University) ;
  • Sung, Jai Ki (College of Agriculture, Seoul National University) ;
  • Rhee, Young So (College of Agriculture, Seoul National University) ;
  • Lee, Yong-Bin (College of Agriculture, Seoul National University) ;
  • Chung, Yung Chai (College of Agriculture, Choong Nam National University)
  • Published : 1967.10.22
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Abstract

An experiment was performed in order to investigate the effects of daily oral administration of propylthiouracil per kg body weight on the metabolic rate and the thyroidal activity in ten, Korean native goats by using the Benedict-Roth Metabolism apparatus and the radioactive iodine-131 in the average environmental temperature at $5.7^{\circ}C$. The results obtained were as follows: 1) The mean metabolic rates of the treated group and the control group were $34.5Kcal./m^2/hr.$ and $33.8Kcal./m^2/hr.$ 2) The peak of thyroidal uptake $I^{131}$ rate in the treated group was 20.12% in 48 hrs., following administration of $I^{131}$ and it was 22.62% in the control group in 96 hrs., Highly significant difference was observed(P<0.01).

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