대한핵의학회지 (The Korean Journal of Nuclear Medicine)

대한핵의학회 (The Korean Society of Nuclear Medicine)
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만성골수성(慢性骨髓性) 백혈병(白血病)의 Ferrokinetics

Ferrokinetics on Chronic Myelogenous Leukemia

  • 황기석 (경북대학교 의과대학 동위원소과) ;
  • 정창근 (경북대학교 의과대학 동위원소과) ;
  • 이재창 (경북대학교 의과대학 동위원소과)
  • Whang, Kee-Suk (Radioisotope Laboratory Kyungpook Notional University, School of Medicine) ;
  • Chung, Chang-Keun (Radioisotope Laboratory Kyungpook Notional University, School of Medicine) ;
  • Lee, Jae-Chang (Radioisotope Laboratory Kyungpook Notional University, School of Medicine)
  • 발행 : 1967.11.10
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초록

Ferrokinetcs by Pollycove's method on 2 cases of Chronic myelogenous leukemia were presented in order to study the erythropoietic function and pathogenesis of anemia. The results are as follows. (1) The daily hemoglobin syntheses were slightly elevated. Both the mean effective hemoglobinization time and mean erythron life span were shortened. The maximum net ROC incorporations of $^{59}Fe$ weere decreased. The in vivo surface measurements of radioactivity over liver, spleen, and sacral bone marrow revealed findings consistant with hemolysis and extramedullary hematopoies. (2) Based upon those findings it is assumed that anemia in chronic myelogenous leukemia may result from hemolysis and inadequate compensation to the developing anemia.

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