Respiratory effect of Ginnol on rabbits

Ginnol이 가토호흡(家兎呼吸)에 미치는 영향(影響)

Ginnol was obtained from Gingko Biloba L. by purification of its extract. Author observed the hyperventillation effect on pentobarbital anesthetized rabbit with Ginnol but there was no significant change in blood pressure. Morphine sulfate, even in large doses, did not alter the hyperventillation effect of Ginnol on rabbit. Blood chemistry of Ginnol treated rabbit showed slight increase in blood pH but within a physiological normal range, and increased total $CO_2$ content. While slight decreased $pCO_2$, increased ${HCO_3}^-$ and decreased $H_2CO_3$ and with decreased blood $Cl^-$ meant an uncompensatory alkalotic change but methemoglobin was not detected.