Reserpine 전처리가토(前處置家兎)에 있어서의 Bradykinin의 강압효과(降壓效果)

Depressor Effect of Bradykinin in Rabbits Pretreated with Reserpine.

The blood pressure responses following repeated injection of bradykinin were observed in the unanesthetized rabbits or rabbits treated with reserpine (0.5mg/kg IV) 24 hours previously. Bradykinin (0.5ug/kg) was injected intravenously at 10 minutes intervals for 5 times. In both groups of rabbits no appreciable changes in the depressor responses to each injection of bradykinin were observed. In the rabbits pretreated with reserpine, however, the more pronounced depressor responses to bradykinin was elicited.