한국동물학회지 (The Korean Journal of Zoology)
- 제8권2호
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- Pages.33-36
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- 1965
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- 0440-2510(pISSN)
X-선에 의한 돌연변이 빈도에 미치는 Colchicine의 영향
The Modification of X-ray induced Mutation in Paramecium by Pre-and Post-irradiation Treatment with Colchicine.
초록
We have carried out a study on the modification of the frequency of X-ray induced lethal and slow growing mutations by colchincine treatment before and after X-ray irradiation in Paramecium aurelia. 1. Lethal and slow-growing mutation induced by X-ray in Paramecium aurelia were reduced by colchicine treatment. 2. The effects of colchicine on the X-ray induced mutations were remarkable in the radiosensitive stages of cell division. 3. The pre-irradiation treatment with colchicine showed no significant influence on the frequency of mutations. 4. It is believed that the reduction of mutation induced by X-ray after treatment with colchicine was due to the fact that the delay of the cell division allowed more time for the pre-mutational damage to recover.
키워드