Pharmacological Study of Components of L. pseudo-laeve Nakai.

Lycoctonum 속식물성분의 약리학적연구 I

  • Published : 1963.12.01

Abstract

Crystal A and B were isolated from L. pseudo-leave Nakai and their pharmacological action was observed. Crystal A, in dose of 5 * $10^{-4}$ - 5 * $10^{-5}g/ml$, stimulated excised frog heat but at 2.5 * $10^{-6}$ - 0.5 * $10^{-5}g/ml$ of crystal B, depressant effect was observed. Mild stimulation of rhythmicity of exercised rabbit intestine was produced by 1 * $10^{-4}$ g/ml of crystal A and 2 * $10^{-4}g/ml$ of crystal B. Marked depression of tone was produced by 2 * $10^{-4}g/ml$ of crystal A, antagonizing by pilocarpine. Crystal B(4 * $10^{-4}gm/l)produced$ mild stimulation, followed by depression of tone. No curare-like action on excised frog abdominal muscle was elicited with both substances.

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