A Study on the Pharmacological Actions of Lycaconitine, an Alkaloid of Radix Jingyu with Emphasis on Toxicologic Aspects

진구성분 Lycaconitine의 약리작용(藥理作用)에 관한 연구(硏究)

Although Lycaconitine, one of the alkaloids of Radix Jingyu, had been identified in 1884, its use in practice has not been known probably because of our limited knowledge on pharmacologic actions of the drug. Recently repellent efficacy of Lycaconitine against Korean cattle ticks and goat ticks was demonstrated. Obviously, there in a need to investigate toxicologic aspects of Lycaconitine before its widespread use for the control of animal ticks can be attempted. As will be reported in this paper, Lycaconitine Shows a wide margin of safety in the concentration applied as cattle or goat tick repellent.