Acknowledgement
본 연구는 수원대학교 교내연구진흥기금의 지원에 의해 이루어진 결과로 이에 감사드립니다.
Kadsura heteroclita (Roxb.) Craib and Eichhornia crassipes (Mart.) Solms. have been known to give effects on pimple. Jatropha gossypiifolia L., Anisomeles indica (L.) Kuntze, Kadsura heteroclita (Roxb.) Craib extracts have been used for cough cold for a long time. To test whether Jatropha, Anisomeles, Kadsura and Eichhornia have anti-oxidant acitivity, we performed DPPH assay. Jatropha showed 91.98% anti-oxidant activity and Anisomeles, Eichhornia and Kasuda showed 47.91%, 47.35% and 32.00% anti-oxidant activity, respectively, compared to Ascorbic acid control. To further determine whether these extracts have any cytotoxic effects, we used MTT assay with these extracts in Raw264.7 cells. Jatropha showed 45.10% survival rate and Anisomeles, Eichhornia and Kasuda showed 76.78%, 86.24% and 82.88% survival rate, respectively, compared to negative control. Taken together, these results suggest that Jatropha showed higher anti-oxidant activity than other plant extracts, however it has cytotoxic effect. Therefore, we consider Anisomeles, Eichhornia and Kasuda extracts might be a good candidate to develop as a therapeutic agent with higher anti-oxidant acitivity and lower cytotoxic effects among the tested plant extracts.
본 연구는 수원대학교 교내연구진흥기금의 지원에 의해 이루어진 결과로 이에 감사드립니다.