과제정보
본 연구는 국내 육성 감자 품종 부산물의 생리 활성 구명 및 식품소재 개발사업(사업번호: PJ0160522022)의 지원에 의해 이루어진 결과로 이에 감사드립니다.
한국자원식물학회:학술대회논문집 (Proceedings of the Plant Resources Society of Korea Conference)
- 한국자원식물학회 2022년도 추계학술대회
- /
- Pages.90-90
- /
- 2022
Anti-inflammatory Activity of Complex Saponin Separated from Pueraria flos and Adzuki Beans Mixture Extract
- Jung Hwan Nam (Highland Agriculture Research Institute, National Institute of Crop Science, Rural Development Administration) ;
- Jong Nam Lee (Highland Agriculture Research Institute, National Institute of Crop Science, Rural Development Administration) ;
- Su hyoung Park (Highland Agriculture Research Institute, National Institute of Crop Science, Rural Development Administration) ;
- Su Jeong Kim (Highland Agriculture Research Institute, National Institute of Crop Science, Rural Development Administration) ;
- Hwang Bae Sohn (Highland Agriculture Research Institute, National Institute of Crop Science, Rural Development Administration) ;
- Do Yeon Kim (Highland Agriculture Research Institute, National Institute of Crop Science, Rural Development Administration)
- 발행 : 2022.09.27
초록
Pueraria flos and Adzuki Beans contains several bioactive compounds, such as saponin, oleanolic acid, and flavone. Pueraria flos and Adzuki Beans has traditionally been used to treat disorders of antioxidant activity, diabetes and liver detoxication, and it has antinociceptive and anti-inflammatory properties. However, complex saponin were validity of the anti-inflammatory activity has not been scientifically investigated. In this study, to determine anti-inflammatory activity of complex saponin separated from Pueraria flos and Adzuki Beans mixture extract on nitric oxide and prostaglandinE2 assay. The anti-inflammatory activities of complex saponin separated from Pueraria flos and Adzuki Beans mixture extract were evaluated for inhibitory activities against lipopolysacchride induced nitric oxide and prostaglandinE2 production protein expressions in RAW264.7 cell lines. The complex saponin separated from Pueraria flos and Adzuki Beans mixture extract inhibitory activity for both tests with protein high depressions(%) values showed in the ranges of 50~100 ㎍/ml. Overall, prostaglandinE2 tests had a higher inhibitory effect on inflammation than nitricoxide tests. Theseis result suggest a potential role of complex saponin separated from Pueraria flos and Adzuki Beans mixture extract as source of anti-inflammation agent.
키워드