Prevalence and risk factors of gallbladder polyps among adults on Jeju Island according to genders

성별에 따른 제주도 성인의 담낭용종 유병률 및 위험인자

  • Kwon, Oh-Sung (Dept. of Medical Information, Jeju National University Hospital) ;
  • Lee, Sang-Jun (Dept. of Medicine, Jeju National University School of Medicine) ;
  • Kim, Young-Kyu (Dept. of Surgery, Jeju National University Medical School) ;
  • Jung, Jin-Young (Dept. of Health and IT Convergence, Daejeon Health Institute of Technology)
  • 권오성 (제주대학교병원 의료정보과) ;
  • 이상준 (제주대학교 의학전문대학원 의학과) ;
  • 김영규 (제주대학교 의과대학교 외과학교실) ;
  • 정진영 (대전보건대학교 의료IT융합과)
  • Published : 2021.07.14

Abstract

Gallbladder polyps (GBPs) may be a cause of gallbladder cancer. The known risk factors for GBPs are male gender, obesity, metabolic syndrome, and dyslipidemia. Especially, male gender has been known that it strongly affects on the prevalence of GBPs. Therefore, this study aimed to investigate risk factors affecting the prevalence of GBPs among adults on Jeju Island according to genders. We examined 5,574 subjects who visited a single health-screening center in Jeju between January 2015 and December 2019. Univariate and multiple logistic regression analysis were performed to identify risk factors affecting the prevalence of GBPs. The prevalence of GBPs were 8.9% in male subjects and 8.1% in female subjects, respectively. Multivariate analysis revealed that ≥60 year age (odds ratio [OR] 0.659; P=0.027) and aspartate aminotransferase >32 IU/L (OR 0.658; P=0.009) in male subjects and high-density lipoprotein-cholesterol ≥60 mg/dL (OR 0.514; P=0.013) in female subjects were independent factors affecting the prevalence of GBPs. The prevalence of GBPs in men (8.9%) is comparable to that in women (8.1%) on Jeju Island. Age <60 years and the high level of aspartate aminotransferase in men and the greater level of high-density lipoprotein-cholesterol in women were independent risk factors of GBPs on Jeju Island.

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