Proceedings of the Plant Resources Society of Korea Conference (한국자원식물학회:학술대회논문집)
- 2018.04a
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- Pages.91-91
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- 2018
Anti-inflammatory Effects of Ponciri Fructus Extracts on Raw 264.7 Cells
- Lee, Jin Wook (Department of Biomedical Science, Jungwon University) ;
- Jung, Hyuk-Sang (Department of Anatomy, College of Korean Medicine, Kyung Hee University) ;
- Sohn, Youngjoo (Department of Anatomy, College of Korean Medicine, Kyung Hee University) ;
- Kang, Yoon Joong (Department of Biomedical Science, Jungwon University)
- Published : 2018.04.27
Abstract
Poncirus Fructus (PF) is obtained by drying the trifoliate orange fruit belonging to the Rutaceae family. In our country of medicine, PF has been used as a treatment of indigestion, allergy and inflammation. But Mechanism and medical data for PF is insignificant. Recently, the effect of the study PF of biological activity was reported, such as anti- thrombosis, anti-bacteria, anti-virus, anti- allergic. We investigated that the effect of PF on anti-inflammatory in murine macrophage-like cell line Raw264.7 cells. Our results show that the expression level of Nitric Oxide (NO) and Matrix-metallopeptidase-9 (MMP-9) significantly decreased. Moreover, to determine the expression level of pro-inflammatory cytokines such as Tumor Necrosis Factor (