Proceedings of the Plant Resources Society of Korea Conference (한국자원식물학회:학술대회논문집)
- 2018.04a
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- Pages.13-13
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- 2018
Anti-inflammatory Metabolites of Agrimonia pilosa Ledeb. and Their Mechanism
- Park, Mi Jin (Functional Plant Lab., Department of Horticultural Science, College of Agriculture and Life Sciences, Kyungpook National University) ;
- Ryu, Da Hye (Functional Plant Lab., Department of Horticultural Science, College of Agriculture and Life Sciences, Kyungpook National University) ;
- Cho, Jwa Yeoung (Functional Plant Lab., Department of Horticultural Science, College of Agriculture and Life Sciences, Kyungpook National University) ;
- Kang, Young-Hwa (Functional Plant Lab., Department of Horticultural Science, College of Agriculture and Life Sciences, Kyungpook National University)
- Published : 2018.04.27
Abstract
The anti-inflammatory (INF) compounds (1-15) were isolated from Agrimonia pilosa Ledeb. (APL) by activity-guided isolation technique. The isolated compounds (1-15) were identified as quercetin-7-O-rhanmoside (1), apigenin-7-O-glycoside (2), kaempferol-7-O-glycoside (3), apigenin-7-O-[6"-(butyl)-glycoside] (4), querceitn (5), kaempferol (6), apigenin (7), apigenin-7-O-[6"-(pentyl)-glycoside] (8), agrimonolide (9), agrimonolide-6-O-glucoside (10), desmethylagrimonolide (11), desmethylagrimonolide-6-O-glucoside (12), luteolin (13), vitexin (14) and isovitexin (15). Flavonoids, compound 2, 3, 11, and 14-15 have been found in APL for the first time. Furthermore, two novel flavone derivatives, compound 4 and 8, have been isolated inceptively in plant. In the no cytotoxicity concentration ranges of
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