A case of phenytoin-induced cerebellar atrophy

페니토인 사용에 따른 소뇌 위축 사례

  • Kim, jae-hyeon (Vision University of Jeonju, Jeonju Jesus Hospital Adverse Drug Reaction Committee)
  • 김재현 (전주비전대학교 간호학과, 전주예수병원 의약품 부작용 위원회)
  • Published : 2016.05.20

Abstract

Cerebellar atrophy was found that a patient was taking oral phenytoin for 3 years. 53 years old female patient with General tonic clonic(GTC) type seizure was prescribed phenytoin. In the process, she developed ataxic gate, dysarthria. Brain magnetic resonance imaging(MRI) finding was revealed differential diagnosis cerebellar atrophy. She was prescribed epileptol instead of phenytoin. But leukopenia, thrombocytopenia occurred. As a result, phenytoin restarted. Development of medical state decreased abuse of anticonvulsants. Considering various convulsive disorders, we must give attention to using anticonvulsants.

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