농생명 오믹스데이터 통합 및 표준화

Challenges in Construction of Omics data integration, and its standardization

  • 김도완 (국립농업과학원, 국립군산대학교) ;
  • 이태호 (국립농업과학원, 국립군산대학교) ;
  • 김창국 (국립농업과학원, 국립군산대학교) ;
  • 설영주 (국립농업과학원, 국립군산대학교) ;
  • 이동준 (국립농업과학원, 국립군산대학교) ;
  • 오재현 (국립농업과학원, 국립군산대학교) ;
  • 백정호 (국립농업과학원, 국립군산대학교) ;
  • 이준아 (국립농업과학원, 국립군산대학교) ;
  • 이홍로 (국립농업과학원, 국립군산대학교)
  • Kim, Do-Wan (Genomics Div., Depatment of Agricultural Bio-resource, National Academy of Agricultural Science, RDA, Computer Information Engineering, Kunsan National University) ;
  • Lee, Tae-Ho (Genomics Div., Depatment of Agricultural Bio-resource, National Academy of Agricultural Science, RDA, Computer Information Engineering, Kunsan National University) ;
  • Kim, Chang-Kug (Genomics Div., Depatment of Agricultural Bio-resource, National Academy of Agricultural Science, RDA, Computer Information Engineering, Kunsan National University) ;
  • Seol, Young-Joo (Genomics Div., Depatment of Agricultural Bio-resource, National Academy of Agricultural Science, RDA, Computer Information Engineering, Kunsan National University) ;
  • Lee, Dong-Jun (Genomics Div., Depatment of Agricultural Bio-resource, National Academy of Agricultural Science, RDA, Computer Information Engineering, Kunsan National University) ;
  • Oh, Jae-Hyeon (Genomics Div., Depatment of Agricultural Bio-resource, National Academy of Agricultural Science, RDA, Computer Information Engineering, Kunsan National University) ;
  • Beak, Jung-Ho (Genomics Div., Depatment of Agricultural Bio-resource, National Academy of Agricultural Science, RDA, Computer Information Engineering, Kunsan National University) ;
  • Kim, Juna (Genomics Div., Depatment of Agricultural Bio-resource, National Academy of Agricultural Science, RDA, Computer Information Engineering, Kunsan National University) ;
  • Lee, Hong-Ro (Genomics Div., Depatment of Agricultural Bio-resource, National Academy of Agricultural Science, RDA, Computer Information Engineering, Kunsan National University)
  • 발행 : 2015.05.26

초록

유전체 염기서열 분석비용이 크게 감소하면서 유전체 정보 생산이 본격화됨에 따라 시스템 생물학 기반의 통합 및 표준화된 오믹스 데이터베이스 구축이 필요하다. 이에 따라 현재 진행중인 연구 수행의 결과로 얻어진 차세대유전체서열(NGS) 및 전사체(transcriptome) 등의 대용량 정보를 수집하였고 이를 표준화 형식에 맞춰 농업생명공학정보센터(NABIC)에 등록하였다. 또한 농업생명자원 생물정보를 품목별, 개체별로 통합 저장소를 구축하였으며 농업생명자원 생물정보를 품목별, 개체별로 통합 저장소를 구축하였다. 농업생명공학정보센터 오믹스 정보등록시스템 서비스와의 연계 및 확충작업을 하기위해 시스템 기능 개선 및 유지보수 작업을 수행하였다.

We performed integration and standardization of the omics data related agriculture. To do this, we requires progressed computational methods and bioinformatics infrastructures for integration, standardization, mining, and analysis. It makes easier biological knowledge to find. we potentialize registration a row and processed data in NABIC (National Agricultural Biotechnology Information Center) and its processed analysis results were offered related researchers. And we also provided various analysis pipelines, NGS analysis (Reference assembly, RNA-seq), GWAS, Microbial community analysis. In addition, the our system was carried out based on the design and build the quality assurance in management omics information system and constructed the infrastructure for utilization of omics analyze system. We carried out major improvement quality of omics information system. First is Improvement quality of registration category for omics based information. Second is data processing and development platform for web UI about related omics data. Third is development of proprietary management information for omics registration database. Forth is management and development of the statistics module producers about omics data. Last is Improvement the standard upload/ download module for Large omics Registration information.

키워드