한국진공학회:학술대회논문집 (Proceedings of the Korean Vacuum Society Conference)
- 한국진공학회 2009년도 제38회 동계학술대회 초록집
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- Pages.43-43
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- 2010
Direct treatment on live and cancer cells & process innovation of bio-sensor using atmospheric pressure plasma system with low-temperature arc-free unit
- Lee, Keun-Ho (PSM R&D Institute, PSM Inc.) ;
- Lee, Hae-Ryong (PSM R&D Institute, PSM Inc.) ;
- Jun, Seung-Ik (PSM R&D Institute, PSM Inc.) ;
- Bahn, Jae-Hoon (Department of Pathobiology, College of Veterinary Medicine, The University of Tennessee) ;
- Baek, Seung-J. (Department of Pathobiology, College of Veterinary Medicine, The University of Tennessee)
- 발행 : 2010.02.17
초록
We have characterized the parametric and functional properties of live cell and cancer cell according to plasma treatment conditions using Atmospheric Pressure (AP) Plasma with uniquely designed low temperature arc-free unit. AP plasma system showed very highly efficient capabilities of reacting and interfacing directly with live and cancer cells. The parametric results with the types of gases, applied power, applied gap, and process times on cells will be presented in accordance with functional studies of the works. The growth of cancer cells is directly influenced by AP plasma exposure with evaluating plasma conditions in several human cancer cells and understanding how plasma exposure alters molecular signaling pathways. The cells exhibit a slower or faster growth rates compared with untreated cells, depending on the cell types. These results strongly support the conclusion that alterations in one or more of each gene are responsible, at least in part, for plasma-induced apoptosis in cancer cells. In addition, it also will be presented that AP plasma has an important role for the improvement of sensor performance due to excellent interface property between enzyme and metal electrode for bio sensor manufacturing process.
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