A Simultaneous NIRS-EEG Study of Seizure in the Mouse Brain

  • Lee, Seung-Duk (Department of Biomedical Engineering, Yonsei University) ;
  • Lee, Min-Ah (Korea Institute of Science and Technology, Center for neural science) ;
  • Koh, Dalk-Won (Department of Biomedical Engineering, Yonsei University) ;
  • Kim, Beop-Min (Department of Biomedical Engineering, Yonsei University) ;
  • Choi, Jee-Hyun (Korea Institute of Science and Technology, Center for neural science)
  • Published : 2008.07.01

Abstract

We measured hemodynamic responses of seizure in the mouse brain using frequencydomain near infrared spectroscopy (NIRS) and electroencephalogram (EEG). We adapted microfabricated optical holder for consistent contact of the optical fiber to the mouse brain. Our results show that the cerebral oxygenation and hemodynamics of mice can be stably monitored with EEG in the mouse brain.

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