Measurement of Time response of Calcium Ion in MG-63 Cells Induced by Shear Stress

전단응력에 의한 골육종 세포의 칼슘이온 시응답 특성 측정

This paper presents the time responses of calcium ($Ca^{2+}$) ion concentration of MG-63 cells induced by a constant shear stress in micro channel were observed in the real time. Most of cells have similar rising time. There were some time delays because of the initial position of the cell in the micro channel along the pressure-driven fluid flow. The concentration of $Ca^{2+}$ exponentially decreased while time constant of each profile did not have any relation to the peak value of concentration.