환자의 박동형 심장의 폐순환 혈류 모델링에 대한 연구

Hemodynamic Modeling of the Pulsatile Cardiac Pulmonary Perfusion for the Patient's Heart

  • 김종세 (강원대학교 기계메카트로닉스공학부 대학원) ;
  • 김문수 (강원대학교 기계메카트로닉스공학부) ;
  • 최성욱 (강원대학교 기계메카트로닉스공학부)
  • 발행 : 2008.11.05

초록

Pulsatile Extracorporeal Membrane Oxygenation(ECMO) can mitigate the heart load and raise the patient's blood perfusion. But If the ECMO pulsate the blood flow during the systolic period, It can burden to the patient's heart. To avoid the heart injury, we have to consider the relation between output of ECMO, hemodynamic states and heart movement. To raise the efficacy of the pulsatile ECMO, we investigated the coronary perfusion, cardiac muscle tension and hemodynamic states during the ECMO perfusion by using the mathematical model of human blood circulatory system and ECMO. The outflow data of the pulsatile ECMO(T-PLS, Bioheartkorea, Korea) was obtained in vitro experiments. According to the phase and pumping rate of the ECMO, the heart's load and coronary perfusion could be adjusted to the proper levels. The results of the human- ECMO lumped parameter model showed that the synchronizing operation of the pulsatile ECLS can be helpful at stabilizing the patient's hemodynamic states.

키워드