Proceedings of the KSME Conference (대한기계학회:학술대회논문집)
- 2008.11a
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- Pages.1655-1659
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- 2008
Simulation Study on the Efficacy of Toxin Removal by Pulsatile Flow in Blood Purification Systems that use Semipermeable Membranes
- Lim, Ki-Moo (Division of Mechanical Engineering & Mechatronics, Kangwon Univ.) ;
- Shim, Eun-Bo (Division of Mechanical Engineering & Mechatronics, Kangwon Univ.)
- Published : 2008.11.05
Abstract
Using numerical models, we investigated the efficiency of toxin removal using pulsatile flow in blood purification systems that use semipermeable membranes. The model consisted of a three-compartmental mass transfer model for the inside body and a solute kinetics model for the dialyzer. The model predicted the toxin concentration inside the body during blood purification therapy, and the toxin removal efficiencies at different flow configurations were compared quantitatively. According to the simulation results, the clearances of urea and
Keywords
- Blood purification system;
- Semipermeable;
- Numerical model;
- Hemofiltration;
- High flux dialysis;
- Hemodiafiltration;
- Pulsatile pump