Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference (한국전기전자재료학회:학술대회논문집)
- 2006.06a
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- Pages.402-403
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- 2006
Genome Detection Using an DNA Chip Array and Non-labeling DNA
비수식화 바이오칩 및 유전자 검출
- Choi, Yong-Sung (Department of Electrical Engineering, DongShin University) ;
- Lee, Kyung-Sup (Department of Electrical Engineering, DongShin University)
- Published : 2006.06.22
Abstract
This research aims to develop the multiple channel electrochemical DNA chip using microfabrication technology. At first, we fabricated a high integration type DNA chip array by lithography technology. Several probe DNAs consisting of thiol group at their 5-end were immobilized on the gold electrodes. Then target DNAs were hybridized and reacted. Cyclic voltammetry showed a difference between target DNA and control DNA in the anodic peak current values. Therefore, it is able to detect a plural genes electrochemically after immobilization of a plural probe DNA and hybridization of non-labeling target DNA on the electrodes simultaneously. It suggested that this DNA chip could recognize the sequence specific genes.