Proceedings of the Korean Powder Metallurgy Institute Conference (한국분말야금학회:학술대회논문집)

The Korean Powder Metallurgy & Materials Institute (한국분말재료학회 (*구 분말야금학회))
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The Effect of Chitosan on Hydroxyapatite Precipitation

  • Hatim, Zineb (Laboratoire d'Electrochimie et Biomateriaux, Faculte des Sciences. Universite Chouaib Doukkali.) ;
  • Bakasse, Mina (Laboratoire d'Electrochimie et Biomateriaux, Faculte des Sciences. Universite Chouaib Doukkali.) ;
  • Kheribech, Abdelmoula (Laboratoire d'Electrochimie et Biomateriaux, Faculte des Sciences. Universite Chouaib Doukkali.) ;
  • Abida, Fatima (Laboratoire d'Electrochimie et Biomateriaux, Faculte des Sciences. Universite Chouaib Doukkali.) ;
  • Bourouisse, Abderrahim (Laboratoire d'Electrochimie et Biomateriaux, Faculte des Sciences. Universite Chouaib Doukkali.)
  • Published : 2006.09.24
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Abstract

The process of coprecipitation of biocomposite hydroxyapatite/chitosan from aqueous solution at low temperature in alkali environnement was examined. We have shown that initially we have the formation of amorphous octocalcium phosphates $(Ca_8(HPO_4)(PO_4)_5,\;nH_2O:\;OCP)$ and the transferring from OCP to amorphous calcium phosphate $(Ca_9(PO_4)_3,\;nH_2O:\;TCP)$, and then from TCP to calcium-deficient hydroxyapatite $(Ca_{10-X}\;(HPO_4)_X(PO_4)_{6-x}(OH)_{2-X}\;:\;ACP)$ and hydroxyapatite $(Ca_{10}(PO_4)_6(OH)_2\;:\;HAP)$. The transformation of ACP to HAP was inhibited in the presence of chitosan. The result suggests that there is an affinity binding between ACP and chitosan and subsequently blocking the active growth site of ACP.

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