Effect of CYP2D6 Genetic Polymorphism and Metabolic Inhibition on the Pharmacokinetics and QTc Intervals Ofter Single Oral Administration of Flecainide in Healthy Subjects

  • Lim Kyoung-Soo (Department of Pharmacology and Clinical Pharmacology Unit, Seoul National University College of Medicine and Hospital) ;
  • Kim Jung-Ryul (Department of Pharmacology and Clinical Pharmacology Unit, Seoul National University College of Medicine and Hospital) ;
  • Kim Jae-Woo (Department of Pharmacology and Clinical Pharmacology Unit, Seoul National University College of Medicine and Hospital) ;
  • Kim Bo-Hyung (Department of Pharmacology and Clinical Pharmacology Unit, Seoul National University College of Medicine and Hospital) ;
  • Jeon Ji-Young (Department of Pharmacology and Clinical Pharmacology Unit, Seoul National University College of Medicine and Hospital) ;
  • Chung On-Hee (Department of Pharmacology and Clinical Pharmacology Unit, Seoul National University College of Medicine and Hospital) ;
  • Tae Yu-Mi (Department of Pharmacology and Clinical Pharmacology Unit, Seoul National University College of Medicine and Hospital) ;
  • Cho Joo-Youn (Department of Pharmacology and Clinical Pharmacology Unit, Seoul National University College of Medicine and Hospital) ;
  • Yu Kyung-Sang (Department of Pharmacology and Clinical Pharmacology Unit, Seoul National University College of Medicine and Hospital) ;
  • Jang In-Jin (Department of Pharmacology and Clinical Pharmacology Unit, Seoul National University College of Medicine and Hospital) ;
  • Shin Sang-Goo (Department of Pharmacology and Clinical Pharmacology Unit, Seoul National University College of Medicine and Hospital)
  • Published : 2005.12.01