한국생물정보학회:학술대회논문집 (Proceedings of the Korean Society for Bioinformatics Conference)
- 한국생물정보시스템생물학회 2005년도 BIOINFO 2005
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- Pages.113-117
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- 2005
Searching biologically plausible synteny blocks among multiple genomes
- Hachiya, Tsuyoshi (Department of Biosciences and Informatics, Keio University) ;
- Sakakibara, Yasubumi (Department of Biosciences and Informatics, Keio University)
- 발행 : 2005.09.22
초록
In comparative genome analyses, synteny blocks play important roles for finding ortholog genes, reconstructing phylogenetic tree and predicting genome rearrangement events. In this paper, we propose a novel method to search biologically plausible synteny blocks not only from the viewpoint of finding highly preserved regions but also from the viewpoint of analyzing genome rearrangements. We have applied the method to our experiments on four fungal organisms, and succeeded to obtain some biologically interesting results.
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