Fingernail for the Physiological Indicator of Fluoride Exposure in Korean Children

  • Kho, Young-Lim (Department of Environmental Health, Seoul Health College) ;
  • Hwang, Jung-Hee (School of Public Health, Seoul National University) ;
  • Kim, Sung-Yeon (School of Public Health, Seoul National University) ;
  • Ma, Deuk-Sang (College of Dentistry, Kangnung National University) ;
  • Jung, Se-Hwan (College of Dentistry, Kangnung National University)
  • 발행 : 2004.06.04

초록

This work was based on the hypotheses that fingernail clippings can be used as a biomarker for the subchronic exposure to fluoride. This study was conducted to prove the hypotheses and fingernail clippings were collected form 120 preschool children aged $3{\sim}6$ residing in Jumunjin(community water fluoridation area) and Kangnung(non-fluoridation area). The acid-diffusible fluoride in the fingernail clipping was isolated by the acid-diffusion technique and measured with a fluoride electrode. The mean fingernail fluoride as the children's living area were 4.49ug/g(SD 2.43) to Jumunjin and 2.68ug/g(SD 1.13) to Kangnung. As would be expected, the fluoride concentration in fingernail clippings were significantly different between the two geographical groups(p<0.001) determined by t-test.

키워드