한국정밀공학회:학술대회논문집 (Proceedings of the Korean Society of Precision Engineering Conference)
- 한국정밀공학회 2004년도 추계학술대회 논문집
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- Pages.1176-1179
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- 2004
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- 2005-8446(pISSN)
심근세포 모델을 이용한 심장근육의 역학적 분석
Mechanical Analysis of heart muscle using a computational model of cardiac myocyte
초록
A new cell-cross bridge mechanics model is proposed to analyze the mechanics of heart muscle. Electrophysiology of a cardiac cell is numerically approximated using the previous model of human ventricular myocyte. Ion transports across cell membrane initiated by action potential induce excitation-contraction mechanism in the cell via cross bridge dynamics. Negroni and Lascano model (NL model) is employed to compute the tension of cross bridge closely related to ion dynamics in cytoplasm.
키워드