OPTIMIZATION OF BIPHENILE CHLOROMETHYLATION PROCESS

  • Pak, V.V. (Institute of Plant Substance Chemistry, Uzbekistan Academy of Sciences) ;
  • Karimov, R.K. (Institute of Plant Substance Chemistry, Uzbekistan Academy of Science) ;
  • Shakhidoyatov, Kh.M. (Institute of Plant Substance Chemistry, Uzbekistan Academy of Science) ;
  • Soh, Deawha (Myongji University)
  • Published : 2004.05.01

Abstract

Optimization of the biphenile chloromethylation process with paraphormaldegide has been done in the presence of ZnCl$_2$ with HCI gas by the Box-Wilson method of mathematical planning of experiment. The 4, 4'-( dichloromethyl)-biphenile yield dependence on the biphenile - paraphormaldegide ratio, temperature and reaction duration has been studied. A mathematical model of the process has been developed and optimal conditions for the biphenile chloromethylation procedure has been determined

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