Effects of PTP1B Inhibitors and Taurine on Blood Lipid Profiles in Adolescents Obesity Model Rats

  • Cheong, Sun-Hee (Department of Food and Nutrition, College of Human Ecology, Inha University) ;
  • Hyeongjin Cho (Department of Chemistry, Inha University) ;
  • Chang, Kyung-Ja (Department of Food and Nutrition, College of Human Ecology, Inha University)
  • 발행 : 2004.05.01

초록

The protein, called PTP1B (protein tyrosine phosphatase 1B), joins a list of enzymes that mice are associated with obesity. The purpose of this study was to investigate the effects of PTP1B inhibitors and taurine on blood lipid profiles in adolescents obesity model rats. Three week-old thirty-six male Sprague-Dawley rats were randomly assigned to six groups (high fat diet group; HFD group, high fat diet + taurine group; HF+TR group, high fat diet+PTP1B inhibitor A group; HF+A group, high fat diet+PTP1B inhibitor B; HF+B group, high fat diet+PTP1B inhibitor A+taurine group; HF+A+TR group, high fat diet + PTP1B inhibitor B+taurine group; HF+B+TR group).(omitted)

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