한국생물공학회:학술대회논문집
- 2003.10a
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- Pages.655-659
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- 2003
Preparation of Eudragit coated solid lipid nanoparticles (SLN) for hydrophilic drug delivery
- Han, Sung-Chul (Department of Material & Biochemical Engineering Chonnam National University) ;
- Yoon, Hee-Sun (Department of Material & Biochemical Engineering Chonnam National University) ;
- Lee, Ki-Young (Faculty of Applied Chemical Engineering, Chonnam National University) ;
- Kim, Yeon-Zu (Department of Skin and Beauty, Kwangju Health College & Polymer Engineering, Chonnam National University) ;
- Kim, Dong-Woon (Department of Environmental Science, kwangyang Health college, Nanobiomed Inc.)
- Published : 2003.10.22
Abstract
Solid lipid nanoparticle (SLN) system has been attracted increasing attention during last few years as a potential drug delivery carrier However, the SLN have disadvantage of low encapsulation efficiency for hydrophilic drug. In this study, for increase it's encapsulation efficiency, we prepared the
수용성 약물의 캡슐화 효율을 높이기 위하여 eudragit이 코팅된 SLN을 제조하였고 TEM을 이용하여 그 형태가 양호하게 형성된 것을 확인하였다. DLS를 이용하여 형성된 입자의 분포와 크기를 확인하였으며 옥용산을 포함하는 E-SLN은
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