한국생물공학회:학술대회논문집
- 한국생물공학회 2003년도 생물공학의 동향(XIII)
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- Pages.273-277
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- 2003
Optimization of cell growth and TAPS production by Pichia ciferrii mutant in batch culture
초록
Batch culture of mutant derived from Pichia ciferrii ATCC 14091 was investigated for producing the intracellular tetraacetylphytosphingosine (TAPS). Composite experimental design was used to optimize the composition of the culture medium for maximizing the productivity of TAPS. In this experiment, various culture parameters were investigated that were the effects of temperature, the initial culture pH, the carbon-to-nitrogen ratio, the concentration of trace elements, and the concentration of cofactors. The optimal temperature for cell growth and TAPS synthesis appeared to be
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