한국생물공학회:학술대회논문집
- 한국생물공학회 2003년도 생물공학의 동향(XIII)
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- Pages.263-267
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- 2003
Lovastatin Production in Solid-state Fermention by Aspergillus terreus and Its Application for Animal Feed Additive
- Yoon, Ji-Yong (Hanson Bitech Co., Ltd. IACRI 201, Hannam University) ;
- Han, Kyu-Boem (Hanson Bitech Co., Ltd. IACRI 201, Hannam University)
- 발행 : 2003.10.22
초록
Solid-state fermentation of lovastatin by Aspergillus terreus was investigated using commercially available 1.2 L polypropylene bottle designed for mushroom cultivation. Moist solid raw materials such as com, rice, and soy bean were tested and com was found to be most suitable for an economical production of lovastatin. 50% or higher water addition prior to the sterilization of com was effective for the maximal lovastatin production. About 0.5% (w/w) lovastatin content in dried cells and corn mass was obtained after 20 days of solid-state fermentation at 30
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