한국생물공학회:학술대회논문집

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
권호 표지

The effects of various biotic elicitors on the accumulation of scopolamine and hyoscyamine by adventitious hairy root cultures of Scopolia parviflora

  • Jung, Hee-Young (Department of Forest Science, Gyeongsang National University) ;
  • Kang, Seung-Mi (Department of Forest Science, Gyeongsang National University) ;
  • Kang, Young-Min (Department of Forest Science, Gyeongsang National University) ;
  • Kim, Won-Jung (Department of Forest Science, Gyeongsang National University) ;
  • Min, Ji-Yun (Department of Forest Science, Gyeongsang National University) ;
  • Yun, Dae-Jin (Department of Applied Life Science, Gyeongsang National University) ;
  • Bahk, Jung-Dong (Department of Applied Life Science, Gyeongsang National University) ;
  • Choi, Myung-Suk (Department of Forest Science, Gyeongsang National University)
  • Published : 2003.04.11
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Abstract

Hyoscyamine and scopolamine are the pharmaceutically valuable anticholinergic drugs. The aim of our study is to increase the contents of both hyoscyamine and scopolamine by means of elicitation. Various biotic elicitors derived from 3 fungi and 1 yeast were inoculated to the hairy root cultures. When homogenate and supernatant of elicitors treated with hairy root cultures, that of yeast elicitor was only increased scopolamine production. However, all of the fungal elicitors did not influenced the productions of scopolamine and hyoscyamine. Our results will contribute to mass production of tropane alkaloids by hairy root cultures of Scopolia parviflora.

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