제어로봇시스템학회:학술대회논문집

Institute of Control, Robotics and Systems (제어로봇시스템학회)
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Microfluidic Control for Biological Cell Orientation

  • Namkung, Young-Woo (Microsystem Research Center, Korea Institute of Science and Technology (KIST)) ;
  • Park, Jung-Yul (Microsystem Research Center, Korea Institute of Science and Technology (KIST)) ;
  • Kim, Byung-Kyu (Microsystem Research Center, Korea Institute of Science and Technology (KIST)) ;
  • Park, Jong-Oh (Microsystem Research Center, Korea Institute of Science and Technology (KIST)) ;
  • Kim, Jin-Oh (Department of Information & Control Engineering, Kwangwoon University)
  • Published : 2003.10.22
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Abstract

There is a great demand to manipulate biological cell autonomously since biologist should spend much time to obtain skillful manipulation techniques. For this purpose, we propose a cell chip to control, carry, fix and locate the cell. In this paper, we focus on the cell rotator to rotate individual biological cell based on a micro fluidics technology. The cell rotator consists of injection hole and rotation well to rotate a biological cell properly. Under the variation of flow rate in injection hole, the angular velocity of a biological cell is evaluated to find the feasibility of the proposed rotation method. As a practical experiment, Zebrafish egg is employed. Based on this research, we find the possibility of non-contact rotation way that can highly reduce the damage of the biological cell during manipulation. To realize an autonomous biological cell manipulation, a cell chip with manipulation well and micro channel in this research will be utilized effectively in near future.

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