Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.249.1-249.1
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- 2003
Chitosan-Iron casein succinylate nanoparticles as oral delivery systems: increasing the stability and enhancing the absorption of iron nanoparticles.
- Cho, Jung-Hye (Seoul national university, college of pharmacy) ;
- Oungbho Kwunchit (Seoul national university, college of pharmac) ;
- Park, Jeong-Sook (Seoul national university, college of pharmac) ;
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Kim, Chong-Kook
(Seoul national university, college of pharmacy)
- Published : 2003.10.01
Abstract
The objective of the study was to develop an oral delivery system to increase the stability and efficacy of iron casein succinylate. Aqueous nanoparticles were prepared using complex coacervation of the oppositely charged chitosan and iron casein succinylate with polyethyleneglycol (PEG). The physicochemical properties of nanoparticles were investigated using dynamic light scattering, zeta potential and scanning electron microscopy. Chitosan-iron casein succinylate interactions were investigated in solid state by differential scanning calorimetry (DSC) and FT-IR spectrometry. (omitted)
Keywords